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Some listings on our site may receive compensation, and this influences where, how, and in what order such listings appear on this site.
2026 Ranking · Independently scored · Updated September 8, 2026
Compare the best telehealth companies offering popular GLP-1 weight-loss medications online — including semaglutide and tirzepatide.
From $89/mo
A polished, app-first experience from a household telehealth name, offering oral weight-loss options and access to brand-name GLP-1s.
From From $79/mo
The go-to if you want brand-name GLP-1 medications and help navigating insurance and prior authorization.
From $99/mo membership
A holistic, coaching-led program that pairs medication with nutrition and behavior-change support.
From $99/mo + medication
Built on Noom's psychology-based app, blending GLP-1 medication with daily habit and mindset coaching.
From From ~$149/mo
Straightforward, flat-rate compounded GLP-1 plans with a no-frills sign-up — popular for its simplicity.
From From ~$297/mo
Why it's our #1
TotalRx was the only program to score at the top across all five of our ranking factors — the lowest real entry price, the fastest path to treatment, and unlimited care included, with no insurance required and no hidden fees.
Lowest cost to start
From $89/mo — no insurance, no membership fee, free shipping included.
Fastest to treatment
Same-day clinician review and medication at your door in about two business days.
Care actually included
Unlimited consultations and 24/7 messaging — never an upsell.
No insurance, no surprises
Flat monthly pricing with no insurance, no prior authorizations, and no surprise bills.
Every provider is scored on the same five factors. Our ratings are editorial and independent — compensation never changes a score or a rank.
Real first-month and ongoing cost, transparency, and what's bundled in.
Range of GLP-1 options — semaglutide, tirzepatide, injection and oral.
How fast a clinician reviews you and medication reaches your door.
Access to clinicians, consultations, messaging, and ongoing check-ins.
Licensing, pharmacy sourcing, refund/approval guarantees, and reputation.
GLP-1 receptor agonists like semaglutide and tirzepatide mimic a hormone that regulates appetite and blood sugar. By reducing hunger and slowing digestion, they help many people lose a clinically meaningful amount of weight when paired with diet and lifestyle changes. They're prescribed after a clinician confirms you're a suitable candidate.
TotalRx scored highest across our five ranking factors — especially price and value, speed to treatment, and care included. It offers clinician-prescribed semaglutide from $89/mo and tirzepatide from $129/mo with no insurance required, same-day clinician review, free temperature-controlled shipping, and unlimited ongoing care.
Compounded GLP-1 medications are prepared by licensed pharmacies and prescribed by a clinician after review. Unlike brand-name products, compounded medications are not FDA-approved and do not undergo the same review for safety, effectiveness, and quality. Always discuss the risks and benefits with a licensed clinician before starting any treatment.
No. Most of the providers we reviewed, including our #1 pick, offer flat cash pricing with no insurance required. Some providers (like Ro) can also check your insurance and help with prior authorization for brand-name medications if you prefer that route.
It varies by provider. Our top pick, TotalRx, offers same-day clinician review (typically under 24 hours) with medication shipped in about two business days. Other providers in our ranking range from 1 to 5 days for review.
ProviderCompare is free to read. We may earn a commission when you choose a provider through links on this page. This never changes our editorial ratings, which are based on the published methodology above. See our advertiser disclosure for details.
ProviderCompare is free for readers. We may earn a commission when you choose a provider through links on this page, which supports our research. This does not affect our editorial ratings or rankings, which follow the methodology above.
This page is for general information only and is not medical advice. Always consult a licensed healthcare professional before starting any medication. Compounded GLP-1 medications are not FDA-approved and do not undergo the same review for safety, effectiveness, and quality as brand-name products. Individual results vary. All third-party names and logos are trademarks of their respective owners, shown for comparison and identification only and not implying affiliation or endorsement.
Our #1 Pick: TotalRx
★★★★★ 9.8/10 · from $89/mo